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Ontologies as a critical framework for the vast amounts of data in the postgenomic era: an introduction to the basic concepts and applications of ontologies and ontology languages for the life sciences.
Recent advances in biotechnology, spurred by the Human Genome Project, have resulted in the accumulation of vast amounts of new data. Ontologies―computer-readable, precise formulations of concepts (and the relationship among them) in a given field―are a critical framework for coping with the exponential growth of valuable biological data generated by high-output technologies. This book introduces the key concepts and applications of ontologies and ontology languages in bioinformatics and will be an essential guide for bioinformaticists, computer scientists, and life science researchers.The three parts of Ontologies for Bioinformatics ask, and answer, three pivotal questions: what ontologies are; how ontologies are used; and what ontologies could be (which focuses on how ontologies could be used for reasoning with uncertainty). The authors first introduce the notion of an ontology, from hierarchically organized ontologies to more general network organizations, and survey the best-known ontologies in biology and medicine. They show how to construct and use ontologies, classifying uses into three categories: querying, viewing, and transforming data to serve diverse purposes. Contrasting deductive, or Boolean, logic with inductive reasoning, they describe the goal of a synthesis that supports both styles of reasoning. They discuss Bayesian networks as a way of expressing uncertainty, describe data fusion, and propose that the World Wide Web can be extended to support reasoning with uncertainty. They call this inductive reasoning web the Bayesian web.
"synopsis" may belong to another edition of this title.
About the Author:
Kenneth Baclawski is Associate Professor of Computer Science at Northeastern University.
Review:
--Yi Pan, Chair and Professor, Department of Computer Science, Georgia State University, Editor-in-Chief, "International Journal of Bioinformatics Research and Applications"
--Bo Yuan, Departments of Biomedical Informatics and Pharmacology, The Ohio State University
" Given the current explosion of biological data in multiple dimensions, it is time to think systematically about strategies and techniques to not only store, but also integrate and represent them in knowledge-oriented ways. Ontology is the solution, and this book is an excellent effort to evaluate a number of alternative ontology-exchange languages, and to recommend them for use within the larger bioinformatics community." --Bo Yuan, Departments of Biomedical Informatics and Pharmacology, The Ohio State University
" This timely and important book provides lucid, provocative, and comprehensive coverage of essential topics related to ontologies and their critical applications in bioinformatics. Written by leading experts in the field, the book is readable and highly informative. It is highly recommended for undergraduate and graduate students in biology, computer science, and medicine, as well as for researchers interested in bioinformatics and genomic science." --Yi Pan, Chair and Professor, Department of Computer Science, Georgia State University, Editor-in-Chief, "International Journal of Bioinformatics Research and Applications"
& quot; This timely and important book provides lucid, provocative, and comprehensive coverage of essential topics related to ontologies and their critical applications in bioinformatics. Written by leading experts in the field, the book is readable and highly informative. It is highly recommended for undergraduate and graduate students in biology, computer science, and medicine, as well as for researchers interested in bioinformatics and genomic science.& quot; --Yi Pan, Chair and Professor, Department of Computer Science, Georgia State University, Editor-in-Chief, International Journal of Bioinformatics Research and Applications
& quot; Given the current explosion of biological data in multiple dimensions, it is time to think systematically about strategies and techniques to not only store, but also integrate and represent them in knowledge-oriented ways. Ontology is the solution, and this book is an excellent effort to evaluate a number of alternative ontology-exchange languages, and to recommend them for use within the larger bioinformatics community.& quot; --Bo Yuan, Departments of Biomedical Informatics and Pharmacology, The Ohio State University
"Given the current explosion of biological data in multiple dimensions, it is time to think systematically about strategies and techniques to not only store, but also integrate and represent them in knowledge-oriented ways. Ontology is the solution, and this book is an excellent effort to evaluate a number of alternative ontology-exchange languages, and to recommend them for use within the larger bioinformatics community."--Bo Yuan, Departments of Biomedical Informatics and Pharmacology, The Ohio State University
"This timely and important book provides lucid, provocative, and comprehensive coverage of essential topics related to ontologies and their critical applications in bioinformatics. Written by leading experts in the field, the book is readable and highly informative. It is highly recommended for undergraduate and graduate students in biology, computer science, and medicine, as well as for researchers interested in bioinformatics and genomic science."--Yi Pan, Chair and Professor, Department of Computer Science, Georgia State University, Editor-in-Chief, "International Journal of Bioinformatics Research and Applications"
--Bo Yuan, Departments of Biomedical Informatics and Pharmacology, The Ohio State University
" Given the current explosion of biological data in multiple dimensions, it is time to think systematically about strategies and techniques to not only store, but also integrate and represent them in knowledge-oriented ways. Ontology is the solution, and this book is an excellent effort to evaluate a number of alternative ontology-exchange languages, and to recommend them for use within the larger bioinformatics community." --Bo Yuan, Departments of Biomedical Informatics and Pharmacology, The Ohio State University
" This timely and important book provides lucid, provocative, and comprehensive coverage of essential topics related to ontologies and their critical applications in bioinformatics. Written by leading experts in the field, the book is readable and highly informative. It is highly recommended for undergraduate and graduate students in biology, computer science, and medicine, as well as for researchers interested in bioinformatics and genomic science." --Yi Pan, Chair and Professor, Department of Computer Science, Georgia State University, Editor-in-Chief, "International Journal of Bioinformatics Research and Applications"
& quot; This timely and important book provides lucid, provocative, and comprehensive coverage of essential topics related to ontologies and their critical applications in bioinformatics. Written by leading experts in the field, the book is readable and highly informative. It is highly recommended for undergraduate and graduate students in biology, computer science, and medicine, as well as for researchers interested in bioinformatics and genomic science.& quot; --Yi Pan, Chair and Professor, Department of Computer Science, Georgia State University, Editor-in-Chief, International Journal of Bioinformatics Research and Applications
& quot; Given the current explosion of biological data in multiple dimensions, it is time to think systematically about strategies and techniques to not only store, but also integrate and represent them in knowledge-oriented ways. Ontology is the solution, and this book is an excellent effort to evaluate a number of alternative ontology-exchange languages, and to recommend them for use within the larger bioinformatics community.& quot; --Bo Yuan, Departments of Biomedical Informatics and Pharmacology, The Ohio State University
"Given the current explosion of biological data in multiple dimensions, it is time to think systematically about strategies and techniques to not only store, but also integrate and represent them in knowledge-oriented ways. Ontology is the solution, and this book is an excellent effort to evaluate a number of alternative ontology-exchange languages, and to recommend them for use within the larger bioinformatics community."--Bo Yuan, Departments of Biomedical Informatics and Pharmacology, The Ohio State University
"This timely and important book provides lucid, provocative, and comprehensive coverage of essential topics related to ontologies and their critical applications in bioinformatics. Written by leading experts in the field, the book is readable and highly informative. It is highly recommended for undergraduate and graduate students in biology, computer science, and medicine, as well as for researchers interested in bioinformatics and genomic science."--Yi Pan, Chair and Professor, Department of Computer Science, Georgia State University, Editor-in-Chief, "International Journal of Bioinformatics Research and Applications"
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- PublisherMIT Press
- Publication date2005
- ISBN 10 0262025914
- ISBN 13 9780262025911
- BindingHardcover
- Edition number1
- Number of pages424
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